Plans have been unveiled to make Wales a global centre of excellence and leader in the production of life-saving cancer-treating substances.
Radioisotopes are radioactive atoms used to diagnose and treat cancer.
The Welsh government said nuclear medicine in the UK, Europe and beyond will face a supply crisis by 2030 if nothing was done.
It wants the UK government and other partners to help fund the multi-million pound plan which could create 200 jobs.
The Welsh government wants to secure the supply of medical radioisotopes for Wales and the UK through the development of a project called the Advanced Radioisotope Technology for Health Utility Reactor (Arthur).
Based in Trawsfynydd, Gwynedd, the ?400m facility would be a public sector national laboratory with its own nuclear reactor, producing the medical radioisotopes for use in the NHS in Wales, England, Scotland and Northern Ireland.
Wales' Economy Minister Vaughan Gething said: "Our vision is the creation of project Arthur - a world-leading nuclear medicine facility, which will bring together a critical mass of nuclear science research, development and innovation.
"Through this development, not only can Wales become the leading place in the UK for medical radioisotope production - producing life-saving medical radioisotopes that are critical to cancer diagnosis and treatment
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https://www.bbc.co.uk/news/uk-wales-64212469